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Neoadjuvant radiohormonal therapy for oligo-metastatic prostate cancer: safety and efficacy outcomes from an open-label, dose-escalation, single-center, phase I/II clinical trial

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 231-239 doi: 10.1007/s11684-022-0939-9

Abstract: Robotic-assisted radical prostatectomy was performed after 5‒14 weeks.

Keywords： neoadjuvant     radiotherapy     oligometastatic     prostate cancer     radical prostatectomy    

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Hydroxyl radical-involved cancer therapy via Fenton reactions

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 3,   Pages 345-363 doi: 10.1007/s11705-021-2077-3

Abstract: therapeutic strategies based on H2O2 as a reaction substrate to generate hydroxyl radicalFurthermore, the challenges and future developments of hydroxyl radical-involved cancer therapy are discussed

Keywords： hydroxyl radical     Fenton catalyst     hydrogen peroxide     cancer therapy    

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structured -FeO/MoS effectively activated peroxymonosulfate for efficient abatement of bisphenol A via both radicaland non-radical pathways

Frontiers of Environmental Science & Engineering 2023, Volume 18, Issue 3, doi: 10.1007/s11783-024-1797-2

Abstract:

● Magnetic Co- γ -Fe2O3/MoS2 were prepared via facile hydrothermal methods.

Keywords： Magnetic Co-γ-Fe2O3/MoS2     Hydrothermal method     Bisphenol A     Degradation pathways     Toxicity analysis    

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Non-closure of the peritoneum and subcutaneous tissue at radical hysterectomy: A randomized controlled

Zhou-Fang XIONG MD, Wei-Hong DONG MD, Ze-Hua WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 112-116 doi: 10.1007/s11684-010-0016-7

Abstract: peritoneum and subcutaneous tissue on the clinical outcomes of cervical cancer patients who underwent radicalThe practice of closure of the peritoneum and subcutaneous tissue at radical hysterectomy should be questioned

Keywords： cervical cancer     radical surgery     peritoneum     subcutaneous tissue    

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Bacteria inactivation by sulfate radical: progress and non-negligible disinfection by-products

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1629-9

Abstract:

● Status of inactivation of pathogenic microorganisms by SO4•− is reviewed.

Keywords： Sulfate radicals     Disinfection by-products     Inactivation mechanisms     Bacterial inactivation     Water disinfection    

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Free radical scavenging window of infertile patients with polycystic ovary syndrome: correlation with

Bo Huang, Zhou Li, Xinling Ren, Jihui Ai, Lixia Zhu, Lei Jin

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 247-252 doi: 10.1007/s11684-017-0519-6

Abstract: However, studies analyzing the relationship between the free radical scavenging capacity and embryo qualityThe aim of this study was to evaluate the relationship between the free radical scavenging window of(DPPH), 2,2-azinobis (3-ethylbenzthiazoline-6-sulphonic acid) assay, superoxide radical, and reactiveThe lower control limit of DPPH radical scavenging capacity and upper control limit of ROS level wereThese cut-off values of free radical scavenging activity of follicular fluid could assist embryologists

Keywords： in vitro fertilization     PCOS     free radical     embryo quality    

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Hydroxyl radical intensified Cu

Wenyue Li, Min Chen, Zhaoxiang Zhong, Ming Zhou, Weihong Xing

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 6, doi: 10.1007/s11783-020-1281-6

Abstract: The intensified radical yield, fast mass transfer and nanoparticles high activity all contributed to

Keywords： Ceramic membrane reactor     N     N-dimethylacetamide     Fenton process     Cu2O     Wastewater treatment    

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A pulsed switching peroxi-coagulation process to control hydroxyl radical production and to enhance 2,4

Yaobin Lu, Songli He, Dantong Wang, Siyuan Luo, Aiping Liu, Haiping Luo, Guangli Liu, Renduo Zhang

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 5, doi: 10.1007/s11783-018-1070-7

Abstract:

• A new pulsed switching peroxi-coagulation (PSPC) system was developed.

• The ECT for 2,4-D removal in the PSPC was lower than that in the EF.

• The iron consumption for 2,4-D removal in the PSPC was lower than that in the PC.

Keywords： Pulsed switching peroxi-coagulation system     Energy consumption     Hydroxyl radical production     2     4- Dichlorophenoxyacetic    

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Zero-valent manganese nanoparticles coupled with different strong oxidants for thallium removal from wastewater

Keke Li, Huosheng Li, Tangfu Xiao, Gaosheng Zhang, Aiping Liang, Ping Zhang, Lianhua Lin, Zexin Chen, Xinyu Cao, Jianyou Long

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 2, doi: 10.1007/s11783-019-1213-5

Abstract: • Nano zero-valent manganese (nZVMn, Mn0) is synthesized via borohydrides reduction. • Mn0 combined with persulfate/hypochlorite is effective for Tl removal at pH 6-12. • Mn0 can activate persulfate to form hydroxyl and sulfate radicals. • Oxidation-induced precipitation and surface complexation contribute to Tl removal. • Combined Mn0-oxidants process is promising in the environmental field. Nano zero-valent manganese (nZVMn, Mn0) was prepared through a borohydride reduction method and coupled with different oxidants (persulfate (S2O82−), hypochlorite (ClO−), or hydrogen peroxide (H2O2)) to remove thallium (Tl) from wastewater. The surface of Mn0 was readily oxidized to form a core-shell composite (MnOx@Mn0), which consists of Mn0 as the inner core and MnOx (MnO, Mn2O3, and Mn3O4) as the outer layer. When Mn0 was added alone, effective Tl(I) removal was achieved at high pH levels (>12). The Mn0-H2O2 system was only effective in Tl(I) removal at high pH (>12), while the Mn0-S2O82− or Mn0-ClO− system had excellent Tl(I) removal (>96%) over a broad pH range (4–12). The Mn0-S2O82− oxidation system provided the best resistance to interference from an external organic matrix. The isotherm of Tl(I) removal through the Mn0-S2O82− system followed the Freundlich model. The Mn0 nanomaterials can activate persulfate to produce sulfate radicals and hydroxyl radicals. Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy suggested that oxidation-induced precipitation, surface adsorption, and electrostatic attraction are the main mechanisms for Tl(I) removal resulting from the combination of Mn0 and oxidants. Mn0 coupled with S2O82−/ClO− is a novel and effective technique for Tl(I) removal, and its application in other fields is worthy of further investigation.

Keywords： Nano zero-valent manganese     Thallium     Adsorption     Oxidation     Sulfate radical     Hydroxyl radical    

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Removal of nitric oxide from simulated flue gas using aqueous persulfate with activation of ferrous ethylenediaminetetraacetate in the rotating packed bed

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 4,   Pages 460-469 doi: 10.1007/s11705-022-2224-5

Abstract: Nitric oxide being a major gas pollutant has attracted much attention and various technologies have been developed to reduce NO emission to preserve the environment. Advanced persulfate oxidation technology is a workable and effective choice for wet flue gas denitrification due to its high efficiency and green advantages. However, NO absorption rate is limited and affected by mass transfer limitation of NO and aqueous persulfate in traditional reactors. In this study, a rotating packed bed (RPB) was employed as a gas–liquid absorption device to elevate the NO removal efficiency (ηNO) by aqueous persulfate ((NH4)2S2O8) activated by ferrous ethylenediaminetetraacetate (Fe2+-EDTA). The experimental results regarding the NO absorption were obtained by investigating the effect of various operating parameters on the removal efficiency of NO in RPB. Increasing the concentration of (NH4)2S2O8 and liquid–gas ratio could promoted the oxidation and absorption of NO while the ηNO decreased with the increase of the gas flow and NO concentration. In addition, improving the high gravity factor increased the ηNO and the total volumetric mass transfer coefficient (KGα) which raise the ηNO up to more than 75% under the investigated system. These observations proved that the RPB can enhance the gas–liquid mass transfer process in NO absorption. The correlation formula between KGα and the influencing factors was determined by regression calculation, which is used to guide the industrial scale-up application of the system in NO removal. The presence of O2 also had a negative effect on the NO removal process and through electron spin resonance spectrometer detection and product analysis, it was revealed that Fe2+-EDTA activated (NH4)2S2O8 to produce •SO4–, •OH and •O2–, played a leading role in the oxidation of NO, to produce NO3– as the final product. The obtained results demonstrated a good applicable potential of RPB/PS/Fe2+-EDTA in the removal of NO from flue gases.

Keywords： rotating packed bed     Fe2+-EDTA     sulfate radical     hydroxyl radical     NO removal efficiency    

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Radical versus conservative surgical treatment of liver hydatid cysts: a meta-analysis

Qing Pang, Hao Jin, Zhongran Man, Yong Wang, Song Yang, Zongkuang Li, Yimin Lu, Huichun Liu, Lei Zhou

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 350-359 doi: 10.1007/s11684-017-0559-y

Abstract:

To date, the efficacy of radical surgery (RS) versus conservative surgery (CS) for liver hydatid cysts

Keywords： liver hydatid cysts     radical surgery     conservative surgery     meta-analysis     complications    

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Adjuvant chemotherapy versus adjuvant concurrent chemoradiotherapy after radical surgery for early-stage

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 93-104 doi: 10.1007/s11684-021-0892-z

Abstract: We conducted a prospective study to assess the non-inferiority of adjuvant chemotherapy alone versus adjuvant concurrent chemoradiotherapy (CCRT) as an alternative strategy for patients with early-stage (FIGO 2009 stage IB–IIA) cervical cancer having risk factors after surgery. The condition was assessed in terms of prognosis, adverse effects, and quality of life. This randomized trial involved nine centers across China. Eligible patients were randomized to receive adjuvant chemotherapy or CCRT after surgery. The primary end-point was progression-free survival (PFS). From December 2012 to December 2014, 337 patients were subjected to randomization. Final analysis included 329 patients, including 165 in the adjuvant chemotherapy group and 164 in the adjuvant CCRT group. The median follow-up was 72.1 months. The three-year PFS rates were both 91.9%, and the five-year OS was 90.6% versus 90.0% in adjuvant chemotherapy and CCRT groups, respectively. No significant differences were observed in the PFS or OS between groups. The adjusted HR for PFS was 0.854 (95% confidence interval 0.415–1.757; P = 0.667) favoring adjuvant chemotherapy, excluding the predefined non-inferiority boundary of 1.9. The chemotherapy group showed a tendency toward good quality of life. In comparison with post-operative adjuvant CCRT, adjuvant chemotherapy treatment showed non-inferior efficacy in patients with early-stage cervical cancer having pathological risk factors. Adjuvant chemotherapy alone is a favorable alternative post-operative treatment.

Keywords： chemotherapy     cervical cancer     lymph node metastasis     concurrent chemoradiotherapy     quality of life    

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Light-induced variation in environmentally persistent free radicals and the generation of reactive radical

Yafang Shi, Yunchao Dai, Ziwen Liu, Xiaofeng Nie, Song Zhao, Chi Zhang, Hanzhong Jia

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 6, doi: 10.1007/s11783-020-1285-2

Abstract: . • The “unstable” free radicals induced the formation of reactive radical species. • Reactive radicalsSignificant positive correlations were observed between the concentrations of EPFRs and reactive radical0.98, p<0.05), which suggested that the newly produced EPFRs contributed to the formation of reactive radical

Keywords： Peat     Humic substances     Environmentally persistent free radicals     Light irradiation     Reactive radical species    

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Insights into the electron transfer mechanisms of permanganate activation by carbon nanotube membrane for enhanced micropollutants degradation

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 9, doi: 10.1007/s11783-023-1706-0

Abstract:

● A CNT filter enabled effective KMnO4 activation via facilitated electron transfer.

Keywords： KMnO4     Carbon nanotubes     Non-radical pathway     Electron transfer     Water treatment    

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Enhanced reductive degradation of carbon tetrachloride by carbon dioxide radical anion-based sodium percarbonate

Wenchao Jiang, Ping Tang, Shuguang Lu, Xiang Zhang, Zhaofu Qiu, Qian Sui

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 2, doi: 10.1007/s11783-017-0987-6

Abstract: Scavenging tests indicated that carbon dioxide radical anion (CO2· ) was the dominant reactive oxygen

Keywords： Carbon tetrachloride     Sodium percarbonate     Formic acid     Reductive radicals     Groundwater    

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Title Author Date Type Operation

Neoadjuvant radiohormonal therapy for oligo-metastatic prostate cancer: safety and efficacy outcomes from an open-label, dose-escalation, single-center, phase I/II clinical trial

Journal Article

Hydroxyl radical-involved cancer therapy via Fenton reactions

Journal Article

structured -FeO/MoS effectively activated peroxymonosulfate for efficient abatement of bisphenol A via both radicaland non-radical pathways

Journal Article

Non-closure of the peritoneum and subcutaneous tissue at radical hysterectomy: A randomized controlled

Zhou-Fang XIONG MD, Wei-Hong DONG MD, Ze-Hua WANG MD,

Journal Article

Bacteria inactivation by sulfate radical: progress and non-negligible disinfection by-products

Journal Article

Free radical scavenging window of infertile patients with polycystic ovary syndrome: correlation with

Bo Huang, Zhou Li, Xinling Ren, Jihui Ai, Lixia Zhu, Lei Jin

Journal Article

Hydroxyl radical intensified Cu

Wenyue Li, Min Chen, Zhaoxiang Zhong, Ming Zhou, Weihong Xing

Journal Article

A pulsed switching peroxi-coagulation process to control hydroxyl radical production and to enhance 2,4

Yaobin Lu, Songli He, Dantong Wang, Siyuan Luo, Aiping Liu, Haiping Luo, Guangli Liu, Renduo Zhang

Journal Article

Zero-valent manganese nanoparticles coupled with different strong oxidants for thallium removal from wastewater

Keke Li, Huosheng Li, Tangfu Xiao, Gaosheng Zhang, Aiping Liang, Ping Zhang, Lianhua Lin, Zexin Chen, Xinyu Cao, Jianyou Long

Journal Article

Removal of nitric oxide from simulated flue gas using aqueous persulfate with activation of ferrous ethylenediaminetetraacetate in the rotating packed bed

Journal Article

Radical versus conservative surgical treatment of liver hydatid cysts: a meta-analysis

Qing Pang, Hao Jin, Zhongran Man, Yong Wang, Song Yang, Zongkuang Li, Yimin Lu, Huichun Liu, Lei Zhou

Journal Article

Adjuvant chemotherapy versus adjuvant concurrent chemoradiotherapy after radical surgery for early-stage

Journal Article

Light-induced variation in environmentally persistent free radicals and the generation of reactive radical

Yafang Shi, Yunchao Dai, Ziwen Liu, Xiaofeng Nie, Song Zhao, Chi Zhang, Hanzhong Jia

Journal Article

Insights into the electron transfer mechanisms of permanganate activation by carbon nanotube membrane for enhanced micropollutants degradation

Journal Article

Enhanced reductive degradation of carbon tetrachloride by carbon dioxide radical anion-based sodium percarbonate

Wenchao Jiang, Ping Tang, Shuguang Lu, Xiang Zhang, Zhaofu Qiu, Qian Sui

Journal Article